In this in-depth route guide, you'll find the best ways to travel the 470 kilometre distance from Cartagena to Panama City. Whether you prefer the scenic overnight train, a convenient bus+ferry combo, or the fastest flight option — we've got all the details you need.
There are 2 ways to get from Cartagena to Panama City. You can choose between the flight, sailboat. The most affordable option is by flight, starting from $136. The fastest route is by flight (1h 55m).
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| Transport | Duration | Price | Best For | Popularity |
|---|---|---|---|---|
| FlightFastestBudget | 1h 55m | ($136) | -- | |
| Sailboat | 12h | ($720) | -- |
From ~$136 · 1h 55m - 2h 40m
From ~$720 · 6d 12h
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Carbon Footprint
This 470 km journey produces approximately 42 g CO2 by bus. Taking public transport is one of the lowest-emission ways to travel this route.
Used the Songserm ferry from Koh Samui. Cheaper than Lomprayah but takes a bit longer. Still a perfectly fine crossing. The views approaching Koh Tao are stunning either way.
OOliver S.November 2025Ferry
Train via Surat Thani was our pick. More scenic than Chumphon route and the Lomprayah catamaran from Tapee Pier is very comfortable. Book the special express train for the quickest ride.
The overnight bus with Montanatip was okay but not great. The bus was older and the seats didn't recline much. Ferry portion was fine though. If you're on a tight budget it works.
Took the sleeper train to Chumphon — magical! Woke up to palm trees and transferred to the Lomprayah catamaran. Whole journey felt like an adventure.
Lomprayah bus+ferry combo from Khao San Road was seamless. Departed at 6am, arrived Koh Tao by 3pm. Well organized.
Flew to Koh Samui and took Lomprayah catamaran. More expensive but saved a full day. Worth it if your holiday is short.
Most travelers base themselves near the main beach for easy access to transport, restaurants, and activities.
Popular budget resort with pool, located on Sairee Beach. Walking distance to dive shops and restaurants.
800 THB/night ($24)
Beachfront bungalows with balconies overlooking Sairee Beach. On-site restaurant and dive center.
2,200 THB/night ($66)
Luxury resort with private beach, infinity pool, and spa. Perfect for couples wanting extra comfort.
6,500 THB/night ($195)
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